BMC Cancer

Table 1 Summary of half-maximal inhibitory concentrations (μM) of emodin on hepatocyte lines

From: Emodin inhibits invasion and migration of hepatocellular carcinoma cells via regulating autophagy-mediated degradation of snail and β-catenin

Cell line	L02			HepG2			BEL-7404
Treatment time	24 h	48 h	72 h	24 h	48 h	72 h	24 h	48 h	72 h
IC₅₀	133.05	99.62	73.93	208.71	70.96	52.38	113.57	96.86	46.71
SI^*				0.63	1.40	1.52	1.17	1.02	1.58
Cell line	QGY-7701			Hep3B			BEL-7402
Treatment time	24 h	48 h	72 h	24 h	48 h	72 h	24 h	48 h	72 h
IC₅₀	98.46	71.03	56.99	185.40	115.37	66.11	151.30	84.81	48.09
SI^*	1.35	1.40	1.29	0.71	0.86	1.11	0.87	1.17	1.53

*SI Selectivity index, IC₅₀ value against normal liver cells/IC₅₀ value against HCC

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ISSN: 1471-2407

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