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Fig. 3 | BMC Cancer

Fig. 3

From: An iron metabolism and immune related gene signature for the prediction of clinical outcome and molecular characteristics of triple-negative breast cancer

Fig. 3

Identification and validation of TNBC-IMRGs signature. a The optimal lambda resulted in five nonzero coefficients. b Partial likelihood deviation curve was plotted. c Distribution of the risk score, survival status, and expression profiles of five genes in the TCGA training set. d Kaplan–Meier survival analysis of the high-risk group and low-risk group. e Time-dependent ROC curves at 1-, 3-, and 5-year of the TNBC-IMRGs signature for the training cohort. f, i Distribution of the risk score, survival status, and expression profiles of five genes in GSE2603 and GSE21653 validation set. g-h, j-k Kaplan–Meier survival analysis and ROC curves for the TNBC-IMRGs signature in the GSE2603 and GSE21653. Survival status: 1: dead, 0: alive. Low: low-risk group, High: high-risk group. Time: days. AUC: area under the curve

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