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Table 2 Clinical and socio-demographic factors associated with HT use among poorly differentiated and locally advanced PCa cases which received RT between 2005 and 2014 (n = 2, 349)

From: Suboptimal use of hormonal therapy among German men with localized high-risk prostate Cancer during 2005 to 2015: analysis of registry data

Variables

Received HT

Use of HT

No (n, %)

Yes (n, %)

Crude Risk Ratio (95% CI)

Adjusted Risk Ratio (95% CI)

Age (10 year increase)

  

1.08 (1.01, 1.15)

1.09 (1.02, 1.16)

Tumor gradea

 Low grade

56 (31.6)

121 (68.4)

1.00

1.00

 High grade

867 (41.3)

1, 235 (58.7)

0.86 (0.77, 0.96)

1.07 (0.96, 1.19)

Stage

 Poorly differentiated

731 (44.4)

916 (55.6)

1.00

1.00

 Locally advanced

225 (32.1)

477 (67.9)

1.22 (1.14, 1.31)

1.28 (1.19, 1.37)

German Index of Socioeconomic-deprivationb

 Most affluent

8 (28.6)

20 (71.4)

1.00

1.00

 Medium

446 (40.3)

660 (59.7)

0.84 (0.66, 1.06)

0.75 (0.58, 0.96)

 Least affluent

502 (41.3)

713 (58.7)

0.82 (0.65, 1.04)

0.71 (0.55, 0.92)

Era

 Pre-guideline era

375 (37.7)

620 (62.3)

1.00

1.00

 Guideline era

581 (42.9)

773 (57.1)

1.09 (1.02, 1.17)

1.02 (0.95, 1.09)

Federal States

 Schleswig-Holstein

238 (43.1)

314 (56.9)

1.00

1.00

 Brandenburg

227 (36.7)

392 (63.3)

1.11 (1.01, 1.22)

1.10 (1.00, 1.22)

 Mecklenburg-Vorpommern

131 (40.7)

191 (59.3)

1.04 (0.93, 1.17)

1.09 (0.96, 1.23)

 Saxony

163 (31.2)

360 (68.8)

1.21 (1.10, 1.33)

1.21 (1.10, 1.33)

 Thuringia

197 (59.2)

136 (40.8)

0.72 (0.62, 0.83)

0.72 (0.62, 0.83)

  1. a grading information was missed for about 2.98% (70) of the 2349 cases, b GISD information available only until 2014