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Fig. 3 | BMC Cancer

Fig. 3

From: Quantitative and qualitative changes in platelet traits of sunitinib-treated patients with renal cell carcinoma in relation to circulating sunitinib levels: a proof-of-concept study

Fig. 3

Concentrations of (N-desethyl-)sunitinib correlate with the reduction in platelet count. (A) Correlations between the concentration of sunitinib and N-desethyl-sunitinib in plasma and serum and difference in platelet count (ΔPlt count = Plt count at 2 weeks on treatment – platelet count before treatment). (B) Correlation between the concentration of sunitinib and N-desethyl-sunitinib in isolated platelets (normalized to ng/2.5 × 108 platelets) and difference in platelet count

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