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Table 3 Summary of univariate/multivariate analysis for overall survival in patients with NSCLC (n = 350)

From: Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer

Variables

Univariate analysis

Multivariate analysis

Average survival time (SE)

95%CI

P-value

Exp (B)

95.0%CI

P-value

p-S6

 High expression

44.561 (3.050)

38.583-50.540

0.013*

1.549

1.105-2.173

0.011*

 Low expression

67.500 (5.336)

57.041-77.958

    

Clinical stages

 Stage I-II

68.200 (4.195)

59.977-76.423

0.000*

1.980

1.356-2.893

0.000*

 Stage III

47.862 (3.834)

40.347-55.378

    

LN status

 LNM

44.969 (3.201)

38.695-51.243

0.000*

1.609

1.098-2.360

0.015*

 No LNM

74.932 (5.919)

63.330-86.533

    

Histological type

 SCC

63.464 (5.825)

52.046-74.882

0.240

1.137

0.806-1.603

0.464

 ADC

50.588 (3.367)

43.988-57.188

    

Pathological grade

 Well/moderated

58.662 (3.509)

51.784-65.541

0.003*

1.517

1.094-2.104

0.013*

 Poor

54.226 (4.164)

46.066-62.387

    

Age

  ≤ 50

45.395 (3.633)

38.274-52.515

0.454

1.014

0.718-1.430

0.939

 >50

61.199 (4.064)

53.234-69.165

    

Gender

 Female

54.566 (4.467)

45.810-63.321

0.210

0.718

0.484-1.064

0.099

 Male

57.363 (3.886)

49.747-64.978

    
  1. Abbreviations: CI Confidence interval, Exp(B) Odds ratio, SE Standard error, LNM Lymph node metastasis;
  2. * P < 0.05