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Fig. 2 | BMC Cancer

Fig. 2

From: Novel γδ T cell-based prognostic signature to estimate risk and aid therapy in hepatocellular carcinoma

Fig. 2

Selection of the appropriate soft threshold (power) and construction of the hierarchical clustering tree. A Selection of the soft threshold made the index of scale-free topologies reach 0.90 and analysis of the average connectivity of 1–20 soft threshold power. B γδT cells-related genes with similar expression patterns were merged into the same module using a dynamic tree-cutting algorithm, creating a hierarchical clustering tree. C Heatmap of the correlations between the modules and immune-infiltrating cells (traits). Within every square, the number on the top refers to the coefficient between the cell infiltrating level and corresponding module, and the bottom is the P value. D Volcano plot was delineated to visualize the DEGs. Red represented upregulated and green represented downregulated. E LASSO coefficient profiles of 440 candidate genes. A vertical line is drawn at the value chosen by 10-fold cross-validation. F Ten-time cross-validation for tuning parameter selection in the lasso regression. The vertical lines are plotted based on the optimal data according to the minimum criteria and 1-standard error criterion. The left vertical line represents the 11 genes finally identified

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