Fig. 4
From: RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma
RNF38 inhibits NPC cell migration and invasion in vitro and in vivo. A-B Representative images and quantification of the migration and invasion assays in RNF38-upregulated (RNF38) SUNE-1 and CNE-2 cells and RNF38-downregulated (in-RNF38) 6-10B cells or their controls. C-D Intravenous injection of SUNE-1 cells stably overexpressing or downregulating RNF38 via the tail vein in the xenograft model (n = 6–10). Luminescence of lung metastasis and tumor weight were analysed. E Representative images of the expression of E-cadherin (Left column) and Vimentin (Right column) in xenograft tumors, *p < 0.05, ** p < 0.01