Fig. 5

The predictive value of PD-L1/B7-H4 classifier in predicting CD8+ TILs levels in PaCa. A Representative microphotographs revealed PD-L1 and B7-H4 expression as well as CD8+ TILs levels in PD-L1^high-B7-H4^high, PD-L1^high-B7-H4^low, PD-L1^low-B7-H4^high, and PD-L1^low-B7-H4^low groups using IHC staining. Brown, PD-L1, B7-H4, or CD8. Blue, haematoxylin. Bar = 200 μm. B The levels of CD8+ TILs in these groups in the HPanA150CS02 cohort. PD-L1^high-B7-H4^high: n = 7, PD-L1^high-B7-H4^low: n = 25; PD-L1^low-B7-H4^high: n = 12, PD-L1^low-B7-H4^low: n = 34. C The levels of CD8+ TILs in these groups in the HPanA120Su02 cohort. PD-L1^high-B7-H4^high: n = 8, PD-L1^high-B7-H4^low: n = 24; PD-L1^low-B7-H4^high: n = 17, PD-L1^low-B7-H4^low: n = 8