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Fig. 8 | BMC Cancer

Fig. 8

From: Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota

Fig. 8

Stool from BBR treated mice decreased the expression of pro-inflammatory genes infiltration in AOM/DSS mice. A Significant downregulation in the expression of 26 transcripts involved in inflammatory response by RNA-Sequencing after gavage of BBR treated stool to an AOM mouse model. B A systematic diagram showing major inflammatory pathways implicated by down-regulated genes identified by RNA-Sequencing. C qRT-PCR was performed to verify the changes in expression of genes including Cxcl9, IL-1b, and TNF-α. D Western bolt was performed to confirm the changes in expression of genes including IL-1b, TNF-α and NF-κB (*P < 0.05)

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