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Fig. 4 | BMC Cancer

Fig. 4

From: Overexpression of angiogenic factors and matrix metalloproteinases in the saliva of oral squamous cell carcinoma patients: potential non-invasive diagnostic and therapeutic biomarkers

Fig. 4

MMPs expression analysis by IHC in OSCC tissues and ANT. (A) MMP-2, MMP-3, and MMP-13 IHC images of ANT and OSCC tissue sections. Quantification of (B) MMP-2, (C) MMP-3, and (D) MMP-13 positive area in ANT and OSCC tissue sections, n = 5. Relative mRNA expression of (E) MMP-1, (F) MMP-2, (G) MMP-3, (H) MMP-8, (I) MMP-9, (J) MMP-10, (K) MMP-13, (L) TIMP-1, and (M) TIMP-2 in ANT and OSCC tissue, n = 10. Data are presented as mean ± SD. Significant differences compared with the ANT group, *p < 0.05 and **p < 0.01

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