PAFAH1B3 predicts poor prognosis and promotes progression in lung adenocarcinoma

BMC Cancer

Table 2 Univariate and multivariate analysis of prognostic parameters of clinical LUAD patients using Cox regression

Characteristics	Univariate analysis			Multivariate analysis
Characteristics	HR	P value	95%CI	HR	P value	95%CI
Expression of PAFAH1B3 (low vs.high)	2.240	0.019*	1.141–4.394	1.991	0.046*	1.011–3.921
Age (years) (<60 vs. ≥ 60)	1.394	0.248	0.793–2.450
Gender (male vs.female)	1.320	0.335	0.751–2.320
Primary tumor (T1 vs.T2 vs.T3 + T4)	1.104	0.632	0.736–1.658
Lymph node metastasis (No vs.Yes)	3.389	0.000***	1.824–6.297
Distant metastasis (No vs.Yes)	6.014	0.000***	3.086–11.72
TNM stage (I + II vs.III + IV)	1.937	0.000***	1.431–2.621	1.884	0.000***	1.390–2.552

TNM stage contains lymph node metastasis and distant metastasis, therefore, lymph node metastasis and distant metastasis was not included in the multivariate analysis
CI Confidence interval, HR Hazard ratio. *P < 0.05, **P < 0.01, ***P < 0.001

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