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Table 1 Performance characteristics of mDMRTA2 and mPENK in urine samples

From: A novel and sensitive DNA methylation marker for the urine-based liquid biopsies to detect bladder cancer

Gene

Specificity (%)

Sensitivity (%)

95% CI

Ct value

AUC (95% CI)

mDMRTA2

95

84.37

68.75 to 95.83

≤35.6

0.958 (0.922 to 0.979)

mPENK

95

78.12

60.47 to 89.58

≤35.9

0.937 (0.893 to 0.963)

mDMRTA2 + mPENK

95

84.37

68.75 to 94.79

> 0.564

0.955 (0.905 to 0.976)