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Table 5 Stratified analysis of hazard ratios (HRs) of individual cardiovascular risk factors for breast cancer incidence by race/ethnicity and menopausal status

From: Cardiovascular risk factors and breast cancer incidence in a large middle-aged cohort study

 

White

 

Black

 
 

Premenopause

Postmenopause

Premenopause

Postmenopause

 

HR (95% CI)

HR (95% CI)

HR (95% CI)

HR (95% CI)

Obesity status

 Normal weight

Reference

Reference

Reference

Reference

 Underweight

1.29 (0.18, 9.42)

0.70 (0.22, 2.21)

2.80 (0.27, 28.80)

1.00 (0.13, 7.48)

 Overweight

1.47 (0.99, 2.18)

1.22 (0.92, 1.61)

2.24 (0.63, 7.92)

0.44 (0.24, 0.78)*

 Obesity

0.95 (0.57, 1.57)

1.49 (1.11, 2.01)*

2.02 (0.57, 7.16)

0.86 (0.52, 1.42)

Hypertension

 No

Reference

Reference

Reference

Reference

 Yes

0.96 (0.60, 1.52)

0.94 (0.73, 1.21)

1.82 (0.93, 3.54)

1.22 (0.81, 1.85)

Diabetes

 No

Reference

Reference

Reference

Reference

 Yes

1.72 (0.81, 3.64)

0.86 (0.54, 1.39)

0.74 (0.27, 2.04)

1.46 (0.92, 2.31)

Hypercholesterolemia

 No

Reference

Reference

Reference

Reference

 Yes

0.90 (0.61, 1.34)

0.96 (0.76, 1.20)

0.88 (0.43, 1.79)

1.22 (0.83, 1.79)

Smoking habit

 Never

Reference

Reference

Reference

Reference

 Ever

1.11 (0.75, 1.65)

0.95 (0.72, 1.26)

0.74 (0.28, 1.97)

1.47 (0.90, 2.42)

 Current

0.89 (0.55, 1.44)

1.03 (0.77, 1.37)

1.01 (0.48, 2.19)

1.88 (1.19, 2.96)*

Healthy diet score

 Non-poor

Reference

Reference

Reference

Reference

 Poor

0.89 (0.54, 1.46)

0.96 (0.69, 1.33)

1.24 (0.57, 2.69)

1.61 (1.02, 2.54)*

Physical activity

 Non-poor

Reference

Reference

Reference

Reference

 Poor

1.38 (0.96, 1.99)

1.13 (0.89, 1.44)

1.14 (0.58, 2.25)

0.95 (0.64, 1.41)

  1. Adjusted for education level, income plus cardiovascular risk factor (obesity status, hypertension, diabetes, hypercholesterolemia, smoking habit, healthy diet score, and physical activity)
  2. * P-value < 0.05
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BMC Cancer

ISSN: 1471-2407

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