Cohort 1 No. (%) | Cohort 2 No. (%) | ||
---|---|---|---|
No. of patients N = 26 | No. of patients N = 8 | ||
EGFR-L858R | 19 (73) | EGFR-L858R | 3 (37.5) |
EGFR-19del | 6 (23) | EGFR-19del | 3 (37.5) |
EGFR-L861Q | 1 (4) | EGFR-20ins | 1 (12.5) |
EGFR-amp | 6 (23) | EGFR-L861Q | 1 (12.5) |
TP53 | 16 (62) | TP53 | 5 (62.5) |
CDKN2A | 6 (23) | EGFR-amp | 4 (50) |
CDK4 | 6 (23) | YES1 | 2 (25) |
EGFR-T790M | 4 (15) | MET | 2 (25) |
PIK3CG | 4 (15) | FGF4 | 1 (12.5) |
PIK3CA | 3 (12) | FGF3 | 1 (12.5) |