Table 5 Univariate and multivariate analyses of overall survival

Sex

  Male

1[reference]

  Female

0.823 (0.462-1.465)

0.507

Age (years)

1.020 (0.993-1.049)

0.147

-

-

BMI

0.956 (0.871-1.048)

0.336

-

-

CEA (ng/ml)

1.009 (1.000-1.017)

0.038

1.005 (0.996-1.014)

0.287

CA19-9 (U/ml)

1.003 (1.001-1.004)

<0.001

1.002 (1.001-1.004)

0.003

Tumor location

  Middle and Upper third

1[reference]

  Lower third

1.033 (0.599-1.782)

0.907

  Entire stomach

3.732 (0.492-28.304)

0.203

Histological type

  Well to moderately differentialed

1[reference]

1[reference]

  Poor differentialed

1.441 (0.675-3.077)

0.345

1.282 (0.579-2.834)

0.540

  Signet ring cell

1.014 (0.312-3.294)

0.981

0.547 (0.164-1.829)

0.327

  Mucinous

2.473 (1.157-5.284)

0.019

2.005 (0.917-4.383)

0.081

  Tumor size (mm)

1.006 (0.995-1.018)

0.295

-

-

pTNM stage

  I-II

1[reference]

1[reference]

  III

5.964 (3.108-11.445)

<0.001

4.388 (2.029-9.488)

<0.001

AADAC

  Low expression

1[reference]

1[reference]

  High expression

0.427 (0.248-0.737)

0.002

0.413 (0.235-0.727)

0.002

  mLNR

28.014 (10.216-76.816)

<0.001

2.774 (0.554-13.895)

0.215

Vascular infiltration

  No

1[reference]

1[reference]

  Yes

1.673 (1.021-2.742)

0.041

1.083 (0.617-1.899)

0.782

Nerve infiltration

  No

1[reference]

  Yes

1.412 (0.860-2.320)

0.173

Postoperative chemotherapy

  Yes

1[reference]

  No

1.082 (0.656-1.784)

0.757