Fig. 3

LINC00022 inhibited apoptosis CRC cells. After HCT116, DLD1, and CaCo-2 cells were infected with LINC00022 low expression lentivirus, the apoptosis of HCT116 and DLD1 cells was detected by flow cytometry (a); The protein expression levels of pro caspase 3, cleaved caspase 3, pro PARP, and cleaved PARP were measured using Western blot (b). β-actin served as internal control. Data were presented as mean ± standard deviation (SD). N = 3. ***P < 0.001 vs Lv-anti-NC group or Lv-NC group. PARP, poly(ADP-ribose) polymerase