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Table 1 SNP association analysis: The top 10 SNPs associated with participants who developed KC, and BCCs or SCCs exclusively

From: Associations of keratinocyte cancers with snp variants in the sonic hedgehog pathway

  Chr SNP Gene name A1 A2 P OR L95 U95 Permuted
P
KC 2 rs4848627 GLI2 G A 0.0003 1.53 1.06 2.13 0.0004
9 rs10869721 PRKACG G A 0.0028 1.43 1.13 1.81 0.0044
12 rs3217882 CCND2 G A 0.0141 1.29 1.05 1.58 0.0115
2 rs41268683 LRP2 A G 0.0151 1.72 1.10 2.67 0.0157
7 rs7799478 SMURF1 A G 0.0195 1.28 1.04 1.58 0.0209
2 rs17050378 GLI2 A G 0.0202 1.51 1.06 2.13 0.0171
7 rs59136417 GLI3 A G 0.0275 1.26 1.02 1.54 0.0302
7 rs36113796 GLI3 A C 0.0279 1.40 1.04 1.88 0.0215
4 rs4689304 EVC A G 0.0308 1.25 1.02 1.54 0.0347
9 rs4745514 PRKACG A G 0.0324 1.28 1.02 1.61 0.0260
BCC 12 rs3217882 CCND2 G A 0.004 1.43 1.12 1.82 0.004
1 rs970318 PRKACB A G 0.009 0.72 0.56 0.92 0.009
9 rs10869721 PRKACG G A 0.013 1.43 1.07 1.89 0.017
7 rs6954873 SHH A G 0.018 1.57 1.56 1.59 0.023
2 rs4848627 GLI2 G A 0.022 1.38 1.04 1.83 0.021
1 rs7547892 PRKACB G A 0.025 0.76 0.59 0.96 0.029
3 rs55814436 BOC A G 0.040 0.73 0.54 0.98 0.041
4 rs2279247 EVC G A 0.043 0.75 0.57 0.99 0.076
7 rs36113796 GLI3 A C 0.044 1.43 1.00 2.02 0.035
4 rs4689304 EVC G A 0.055 0.78 0.61 1.00 0.053
SCC 2 rs4848627 GLI2 G A 0.0004 2.12 1.39 3.23 0.0003
18 rs2849380 BCL2 A G 0.0053 1.85 1.19 2.87 0.0075
7 rs35280470 GLI3 A G 0.0073 2.29 1.23 4.25 0.0064
2 rs895485 GLI2 A G 0.0143 0.60 0.40 0.91 0.0139
2 rs17050378 GLI2 A G 0.0269 1.94 107 3.51 0.0208
4 rs735172 EVC G A 0.0274 1.58 1.05 2.37 0.0233
7 rs114615136 GLI3 G A 0.0294 1.85 1.05 3.25 0.0414
3 rs13094203 BOC A G 0.0318 1.68 1.04 2.72 0.0284
5 rs10058728 CSNK1A1 A T 0.0440 1.50 1.01 2.23 0.0714
3 rs73235151 BOC A C 0.0496 0.58 0.34 1.01 0.0743
  1. Chr Chromosome, A1 effect Allele, A2 Non-effect Allele, P P value, L95 95% confidence interval (lower level), U95% 95% confidence interval (upper level)