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Table 3 Multivariate analysis of prognostic factors for the development of high RT-PWL in patients with NPC

From: The prognostic value of weight loss during radiotherapy among patients with nasopharyngeal carcinoma: a large-scale cohort study

Variable

OR

95% CI for OR

P valuea

T stage

 T1-2

Reference

  

 T3-4

1.01

0.74–1.38

0.955

N stage

 N0-1

Reference

  

 N2-3

1.52

1.12–1.94

0.005

LDH, U/Lb

 < 245

Reference

  

 ≥ 245

1.38

0.83–2.29

0.232

EBV DNA, copy/mLb

 < 4000

Reference

  

 ≥ 4000

1.43

1.04–1.96

0.034

Treatment

 RT alone

Reference

  

 CCRT alone

3.29

2.18–4.96

< 0.001

 NAC + CCRT

2.03

1.32–3.13

0.001

  1. Abbreviations: OR Odds ratio, 95% CI 95% confidence interval, LDH Lactate dehydrogenase, EBV Epstein-Barr virus, RT Radiotherapy, CCRT Concurrent chemoradiotherapy, NAC + CCRT Neoadjuvant chemotherapy plus concurrent chemoradiotherapy
  2. a P values were calculated using logistic regression models
  3. b All variables were measured before treatment
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BMC Cancer

ISSN: 1471-2407

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