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Table 2 Intervention and state costs and utilities used in the Markov model

From: Image-guided navigation for locally advanced primary and locally recurrent rectal cancer: evaluation of its early cost-effectiveness

State costs

LARC

SE

LRRC

SE

Distribution

Source

Disease-free

€ 492

€ 63

€ 492

€ 63

Gamma

Expert

Transition from DF to PD

€ 14.883

€ 1.898

€ 13.107

€ 1.672

Gamma

Expert

Progressive disease

€ 585

€ 75

€ 585

€ 75

Gamma

Expert

Intervention costs

Combined LARC & LRRC

SE

Distribution

Source

Surgery

€10.970

€1.399

Gamma

[21]

Addition of navigation

€3.388

€432

Gamma

Expert

Developing 3D model and preoperative CT scan

€ 269

 

[22,23,24]

Additional personnel during OR

€ 197

 

[22, 24]

Navigation system

€ 2.745

 

List prices; expert

Overhead

€ 177

 

[22]

Utilities

Combined LARC & LRRC

SE

Distribution

Source

First cycle

0.70 (n = 63)

0.029

Beta

[C] (1mo survey)

Disease free (subsequent cycles)

0.85 (n = 44)

0.022

Beta

[C] (6mo survey)

Progressive disease (subsequent cycles)

0.77 (n = 14)

0.050

Beta

[C] (6mo survey)

  1. SE Standard error, mo month, [C] Prospective observational cohort study