Integrating BRAFV600E mutation, ultrasonic and clinicopathologic characteristics for predicting the risk of cervical central lymph node metastasis in papillary thyroid carcinoma

Table 3 ROC analysis of the independent factors and equation for predicting cervical CLNM in PTC patients. CI = confidence interval; CLNM = central lymph node metastasis; N = number of papillary thyroid carcinoma; PTC = papillary thyroid carcinoma

	Az	95% CI	Cutoff value	Sensitivity	Specificity
Overall (N = 112)
Age < 55y	0.612	0.504–0.720	Age < 55y	0.862	0.362
Tumor size > 10 mm	0.664	0.561–0.766	Tumor size > 10 mm	0.646	0.681
Microcalcification	0.626	0.520–0.733	Microcalcification	0.785	0.468
Non-Hashimoto’s thyroiditis	0.606	0.497–0.714	Non-Hashimoto’s thyroiditis	0.892	0.319
BRAF mutation	0.637	0.533–0.742	BRAF mutation	0.615	0.660
Predictive equation	0.845	0.771–0.918	0.593	0.738	0.851

ISSN: 1471-2407