Fig. 2
Xenograft tumors of untreated ACHN cells (group 1), ACHN cells treated with scrambled control shRNA (group 2) and cells treated with HMGA2-specific shRNA (group 3) in 4 weeks old female BALB/c nude mice. Tumors began to be observable 18 days after injection of 4 X 106 ACHN cells into the right axillary region of mice and the observation was maintained for 30 days until necropsy. A Pictures of nude mice receiving the above described treatments. B Pictures of xenograft tumors harvested at the time of necropsy. C Quantification of the average tumor sizes of three treatment groups. D Growth curves of xenograft tumors with size being recorded each other day for 30 days. E Curve of the body weight changes of the mice of the three treatment groups