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Fig. 1 | BMC Cancer

Fig. 1

From: CT-707 overcomes hypoxia-mediated sorafenib resistance in Hepatocellular carcinoma by inhibiting YAP signaling

Fig. 1

Hypoxia mediated sorafenib resistance in hepatocellular carcinoma. A SMMC-7721 cell was treated with serial concentrations of sorafenib in normoxia and hypoxia and cell survival were detected using SRB assay. B The IC50 values of sorafenib in normoxia and hypoxia. Data are representative of 3 independent experiments and are expressed as the mean ± SD. The symbols refer to ** P < 0.01 and *** P < 0.001, respectively

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