Fig. 2
From: Activated TAZ induces liver cancer in collaboration with EGFR/HER2 signaling pathways
TAZ alone does not induce cancer. A Schematic illustration of the experimental procedure. Transposons encoding TAZS89A were mixed with plasmids expressing the Sleeping Beauty transposase, and injected via hydrodynamic tail vein injection. B Gross morphology of representative livers expressing TAZS89A and enhanced green fluorescent protein (EGFP, a control). Livers were harvested at 16 weeks following the hydrodynamic injection (n = 5). C Microscopic images showing H&E and IHC staining for pan CK, SOX9, and Ki-67 in sections of livers shown in (B). Scale bar, 50 μm