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Table 1 The characteristics of participants

From: Baseline soluble MICA levels act as a predictive biomarker for the efficacy of regorafenib treatment in colorectal cancer

 

N = 17 (%)

responders

non-responders

P-value

Age (years)

68 (50–77)a

68 (50–77)a

64.5 (63–74)

n.s

Gender

 Male/female

10/7 (59/41)

4/4

6/3

n.s

PS

 0/1

9/8 (53/47)

4/4

5/4

n.s

Total bilirubin (mg/dL)

0.7 (0.1–1.2)a

0.7(0.1–1.1)

0.7(0.4–1.2)

n.s

Serum creatinin (mg/dL)

0.69 (0.51–1.04)a

0.76 (0.51–1.04)

0.61 (0.51–1)

n.s

eGFR (mL/min)

80 (55.4–117.8)a

74.4 (55.4–89.6)

85.2 (57.1–117.8)

n.s

Histology

 Well/moderately/poor,mucinous

7/9/1 (41/53/6)

4/4/0

3/5/1

n.s

Metastatic sites

 Liver/lung/peritoneum/lymph node

11/9/2/4 (65/53/12/24)

4/7/0/1

7/2/2/2

n.s

Treatment lines

 2/3/4/5

1/9/6/1 (6/53/35/6)

0/5/2/1

1/4/4/0

n.s

  1. Treatment lines, The number of treatment lines before regorafenib
  2. eGFR, estimated glomerular filtration rate; PS, ECOG performance status
  3. aMedian (range)