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Table 4 Results of clustering analysis

From: Comprehensive analysis of the associations between clinical factors and outcomes by machine learning, using post marketing surveillance data of cabazitaxel in patients with castration-resistant prostate cancer

Factor

Number of appearances in clusters

Alpha level 0.05

Alpha level 0.01

OS

TTF

OS

TTF

Treatment cycles

5

7

7

7

Lung metastasis

-

-

7

7

Liver metastasis

-

-

7

7

Observation period

5

7

7

7

OS

-

5

-

7

TTF

5

-

7

-

TTF censoring

5

7

7

7

ECOG PS

-

-

6

6

Febrile neutropenia

-

-

4

4

OS censoring

-

-

4

4

Treatment discontinuation (AE)

-

-

4

4

Treatment discontinuation (other)

-

-

4

4

Treatment discontinuation (PD)

4

4

4

4

  1. AE adverse event, ECOG PS Eastern Cooperative Oncology Group performance status, OS overall survival, PD progressive disease, TTF time-to-treatment failure