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Table 3 Results of graphical Markov modeling

From: Comprehensive analysis of the associations between clinical factors and outcomes by machine learning, using post marketing surveillance data of cabazitaxel in patients with castration-resistant prostate cancer

Proportion of estimations in which relationship was present (in 1000 iterations)

Causality association, positive: frequency > 50%

Alpha level 0.05

Alpha level 0.01

OS-associated factors

 TTF

1

1

 OS censoring

0.83

0.77

 ECOG PS

0.52

1

 Observation period

1

1

 Liver metastasis

0.76

0.76

 Neutropenia

0.52

-

TTF-associated factors

 OS

1

1

 TTF censoring

1

1

 Observation period

1

1

 RDI

1

-

  1. ECOG PS Eastern Cooperative Oncology Group performance status, OS overall survival, RDI relative dose intensity, TTF time-to-treatment failure