From: Effect of neoadjuvant iodine-125 brachytherapy upon resection of glioma
Study | No. of patients | Type of gliomas | Implanted dose (Gy) | Median survival |
---|---|---|---|---|
B. Suchorska et al. [20] | 99(primary) 73(recurrence) | Primary and recurrence anaplastic glioma WHOIII | 60(primary), 60(recurrence) | 28.9 months(primary), 21.4 months (recurrence) |
David A. Larson et al. [21] | 38 | Progressive or recurrent glioblastoma multiforme | 300 (at 5-mm depth) | 52 weeks |
Philipp Kickingereder et al. [22] | 103 (primary) 98(recurrence) | Primary and recurrent glioblastoma | 60 | 11.1 months(primary) 10.4(recurrence) |
Patrick Y.Wen et al. [23] | 56 | Glioblastoma | 50 | 22 months (reoperation) 13 months (no further surgery) |
Berstein et al. [24] | 23 | Malignant glioma | 60–70 | 14 months |