Fig. 9From: Proteomics analysis: inhibiting the expression of P62 protein by chloroquine combined with dacarbazine can reduce the malignant progression of uveal melanomaCell biological changes after p62 expression knockdown (a): Among the three plasmids with different targets, the expression of p62 decreased most obviously Interfered by si-P62#2. b Compared to the control group, p62 knockdown can significantly reduce the proliferation rate of 92.1-A; c Scratch assay showed p62 knockdown can reduce the migration ability of 92.1-A cells, statistically significant; d Statistical result of (c). * P < 0.05; e Transwell assay showed p62 knockdown can reduce the invasion ability of 92.1-A cells, statistically significant; f Statistical result of (e). * P < 0.01Back to article page