A multicenter noninferior randomized controlled study comparing the efficacy of laparoscopic versus abdominal radical hysterectomy for cervical cancer (stage IA1 with LVSI, IA2): study protocol of the LAUNCH 1 trial

Table 1 Study procedures and baseline and/or follow-up assessments

Visit Number	Screening for eligibility	Randomization	Blood examination, urinary test, liver and renal function, ECG	Surgical indicators, surgical complications	Gynecological examination	Imaging test	SCCA/CA-125	Cervical liquid-based cytology	HPV test	Adverse events	EORTC QLQ-C30 v3.0; EORTC QLQ-CX24, PRO147(V1.0)
V0	×
V1		×	×	×	×	×	×	×	×	×
V2 (3 mos)					×	×	×			×	×
V3 (6 mos)					×	×	×			×	×
V4 (9 mos)					×	×	×			×	×
V5 (1 yr)					×	×	×	×	×	×	×
V6 (15 mos)					×	×	×			×	×
V7 (1.5 yr)					×	×	×			×	×
V8 (21 mos)					×	×	×			×	×
V9 (2 yr)					×	×	×	×	×	×	×
V10 (2.5 yr)					×	×	×			×	×
V11 (3 yr)					×	×	×	×	×	×	×
V12 (3.5 yr)					×	×	×			×	×
V13 (4 yr)					×	×	×	×	×	×	×
V14 (4.5 yr)					×	×	×			×	×
V15 (5 yr)					×	×	×	×	×	×	×

ECG Electrocardiogram, EORTC European Organization for Research and Treatment of Cancer, QLQ Quality of Life Questionnaire, SCCA SCC antigen test

ISSN: 1471-2407