Clinicopathological and ultrasound features as risk stratification predictors of clinical and pathological nodal status in papillary thyroid carcinoma: a study of 748 patients

Table5 Risk factors for > 5 LN involved in patients with PTC

Variable	Univariate analysis			Multivariate analysis
Variable	OR	95% CI	p	OR	95% CI	p
Age (reference: ≤ 40)	—	—	—
> 40 and ≤ 55	0.50	0.26 ~ 0.98	0.04*
> 55	0.81	0.29 ~ 2.24	0.68
Gender (Female vs. Male)	0.68	0.31 ~ 1.51	0.34
HT (yes vs. no)	0.89	0.31 ~ 2.55	0.82
Nodular goiters (yes vs. no)	0.79	0.42 ~ 1.50	0.47
Multifocality (yes vs. no)	2.66	1.37 ~ 5.17	0.004*	2.70	1.31 ~ 5.56	0.01*
Bilaterality (yes vs. no)	1.75	0.93 ~ 3.29	0.08
Primary tumor size (reference: ≤ 1 cm)	—	—	—
> 1 and ≤ 2 cm	4.45	2.16 ~ 9.15	< 0.001*	2.25	1.05 ~ 4.83	0.05
> 2 cm	11.66	4.66 ~ 29.17	< 0.001*	4.62	1.70 ~ 12.57	0.01*
Capsule contact (yes vs. no)	12.27	2.94 ~ 51.21	0.001*	5.08	1.16 ~ 22.24	0.03*
ETE (yes vs. no)	9.76	4.44 ~ 21.49	< 0.001*	4.80	2.09 ~ 11.06	< 0.001*
E_max	1.03	1.01 ~ 1.05	0.004*
E_mean	1.02	0.99 ~ 1.05	0.17
ER	2.85	1.60 ~ 5.088	< 0.001*

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