Table 5 Toxic side effects in each group of KRAS/NRAS/BRAF WT patients (N)
Toxic side effect, Grade | Chemotherapy alone | Plus Bev | Plus CET | Plus T-mab | ||||
|---|---|---|---|---|---|---|---|---|
1 ~ 2 | 3 ~ 4 | 1 ~ 2 | 3 ~ 4 | 1 ~ 2 | 3 ~ 4 | 1 ~ 2 | 3 ~ 4 | |
Myelosuppression | 6 | 3 | 3 | 1 | 2 | 0 | 2 | 1 |
Gastrointestinal side effects | 13 | 4 | 2 | 1 | 1 | 1 | 9 | 3 |
Liver dysfunction | 3 | 1 | 1 | 0 | 1 | 0 | 2 | 0 |
neurotoxicity | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hand-foot syndrome | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 |
rash | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 0 |
hemorrhages | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
proteinuria | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |