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Fig. 6 | BMC Cancer

Fig. 6

From: Characterization of SN38-resistant T47D breast cancer cell sublines overexpressing BCRP, MRP1, MRP2, MRP3, and MRP4

Fig. 6

Intracelluar mitoxantrone accumulation of the T47D/WT, T47D/SN120 and T47D/SN150 cells. Mitoxantrone accumulation decreased in T47D/SN120 and T47D/SN150 cells, compared to that in T47D/WT cells. However, mitoxantrone accumulation was increased after treatment with BCRP inhibitor (genistein) and ATP deplete cyanide. *, P < 0.05 vs WT (n = 3)

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BMC Cancer

ISSN: 1471-2407

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