From: Pre-diagnostic faecal calprotectin levels in patients with colorectal cancer: a retrospective study
Mean age, years (SD) | 68 (11) |
Gender | |
Women | 44% (n = 55) |
Men | 56% (n = 69) |
Colorectal cancer diagnosed at: | |
Colonoscopy | 92% (n = 114) |
Imaging | 6% (n = 7) |
Surgery | 2% (n = 3) |
Median F-calprotectin level (μg/g) (25th-75th percentile) | 149 (67–392) |
Proportion of patients with: | |
F-calprotectin ≥ 50 μg/g | 79% (n = 98) |
F-calprotectin ≥ 100 μg/g | 60% (n = 74) |
Positive faecal immunchemical test (n = 76)a | 89% (n = 68) |
Tumor characteristics (n = 108)a | |
Low-grade | 85% (n = 92) |
High-grade | 15% (n = 16) |
Non-Mucinous | 85% (n = 92) |
Mucinous | 15% (n = 16) |
Vascular invasion (n = 103)a | 18% (n = 19) |
Perineural growth (n = 103)a | 19% (n = 20) |
TNM classification | |
Tumor (T) (n = 109)a | |
T1 | 3% (n = 3) |
T2 | 19% (n = 21) |
T3 | 61% (n = 66) |
T4a | 9% (n = 10) |
T4b | 8% (n = 9) |
Nodes (N) (n = 106)a | |
N0 | 49% (n = 54) |
N1 | 25% (n = 29) |
N2 | 20% (n = 23) |
Metastasis (M): | |
M0 | 80% (n = 99) |
M1 | 20% (n = 25) |
Tumor Stage | |
I | 20% (n = 24) |
II | 28% (n = 35) |
III | 32% (n = 40) |
IV | 20% (n = 25) |
Tumor localization | |
Right colon | 23% (n = 29) |
Transverse colon | 6% (n = 7) |
Left colon | 29% (n = 36) |
Rectum | 42% (n = 52) |
Median values (25th-75th percentile) of: | |
C-reactive protein (mg/L) (n = 100)a | 4.5 (1.5–13) |
B-haemoglogin (g/L) (n = 121)a | 133 (108–142) |
Mean corpuscular volume (fL) (n = 121)a | 88 (82–92) |
Serum carcinoembryogenic antigen (μg/L) (n = 116)a | 3.1 (1.8–6.9) |
Serum ferritin (μg/L) (n = 48)a | 42 (13–88) |