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Table 1 Clinical characteristics of patients with colorectal cancer who performed a CALPRO® faecal calprotectin (FC) test within three months prior to diagnosis (n = 124)

From: Pre-diagnostic faecal calprotectin levels in patients with colorectal cancer: a retrospective study

Mean age, years (SD)

68 (11)

Gender

Women

44% (n = 55)

Men

56% (n = 69)

Colorectal cancer diagnosed at:

Colonoscopy

92% (n = 114)

Imaging

6% (n = 7)

Surgery

2% (n = 3)

Median F-calprotectin level (μg/g) (25th-75th percentile)

149 (67–392)

Proportion of patients with:

F-calprotectin ≥ 50 μg/g

79% (n = 98)

F-calprotectin ≥ 100 μg/g

60% (n = 74)

Positive faecal immunchemical test (n = 76)a

89% (n = 68)

Tumor characteristics (n = 108)a

Low-grade

85% (n = 92)

High-grade

15% (n = 16)

Non-Mucinous

85% (n = 92)

Mucinous

15% (n = 16)

Vascular invasion (n = 103)a

18% (n = 19)

Perineural growth (n = 103)a

19% (n = 20)

TNM classification

Tumor (T) (n = 109)a

T1

3% (n = 3)

T2

19% (n = 21)

T3

61% (n = 66)

T4a

9% (n = 10)

T4b

8% (n = 9)

Nodes (N) (n = 106)a

N0

49% (n = 54)

N1

25% (n = 29)

N2

20% (n = 23)

Metastasis (M):

M0

80% (n = 99)

M1

20% (n = 25)

Tumor Stage

I

20% (n = 24)

II

28% (n = 35)

III

32% (n = 40)

IV

20% (n = 25)

Tumor localization

Right colon

23% (n = 29)

Transverse colon

6% (n = 7)

Left colon

29% (n = 36)

Rectum

42% (n = 52)

Median values (25th-75th percentile) of:

C-reactive protein (mg/L) (n = 100)a

4.5 (1.5–13)

B-haemoglogin (g/L) (n = 121)a

133 (108–142)

Mean corpuscular volume (fL) (n = 121)a

88 (82–92)

Serum carcinoembryogenic antigen (μg/L) (n = 116)a

3.1 (1.8–6.9)

Serum ferritin (μg/L) (n = 48)a

42 (13–88)

  1. aNumber of subjects with available data