Fig. 1
From: Serum untargeted lipidomics by UHPLC-ESI-HRMS aids the biomarker discovery of colorectal adenoma
Multivariate statistical analysis of differential lipid features between NR and CA groups in both ESI modes. Principal component analysis (PCA) of two groups in ESI+ and ESI- modes, respectively (A, B); orthogonal partial least squares discriminant analysis (OPLS-DA) of the two groups in ESI+ and ESI- modes, respectively (C, D); Overfitting test for OPLS-DA model in ESI+ and ESI- modes, respectively (E, F). Abbreviations: ESI, electrospray ionization; CA, colorectal adenoma; NR, normal control