Fig. 2

Primary prostate adenocarcinoma cell lines form invadopodia. A Cells were seeded on Cy3-conjugated gelatin for 24 h and stained for F-actin and Cortactin. B co-localisation of cortactin, F-actin and gelatin degradation. C Gelatin degradation. D percentage of degraded area underneath total cell area. n = 90 cells. All Data presented represent 3 independent experiments, mean ± S.E.M. Significance was calculated with One-way Anova followed by Tukey’s multiple comparisons test, **p < 0.005. Scale bar = 10 μm