Table 2 Results of univariate and multivariate analysis of overall survival (Cox’s proportional hazard mode)

Sex

 Female

95

1

0.387

1

0.0082

 Male

82

1.2(0.83–1.6)

1.8 (1.2–2.8)

Age, year

  < 75

141

1

0.047

1

0.0099

 ≧75

36

1.5(1.00–2.3)

1.8 (1.2–2.9)

Smoking history

 Current or former smoker

79

1

0.16

1

0.0721

 Never smoker

93

1.3(0.90–1.8)

1.5 (0.96–2.2)

ECOG PS

 0–1

135

1

0.0002

1

0.0008

 2–4

21

2.6(1.6–4.4)

2.7 (1.5–4.7)

Driver mutation

 ALK-Rearranged

22

1

0.0602

1

0.0148

 EGFR-Mutated

155

1.7(0.98–3.1)

2.1 (1.2–3.8)

Stage

 Post operative recurrence

70

1

0.0007

1

 < 0.0001

 Stage III or IV

107

1.9(1.3–2.7)

2.3 (1.5–3.4)

Presence of brain metastasis

 No

132

1

0.0009

1

0.0003

45

1.9(1.3–2.8)

2.1 (1.4–3.2)