Fig. 4

Circ_0058063 knockdown inhibited CDDP resistance in CDDP-resistant BC cells through targeting miR-335-5p. A, B The IC50 value of CDDP was measured by CCK-8 assay for 48 h. C, D Cell proliferation activity was estimated using CCK-8 assay. E, F The cell apoptosis rate was examined by Flow cytometry for 48 h. G The miR-335-5p level was measured by RT-qPCR. H-M The protein levels of B2M, SOX2, OCT4 and NANOG were detected by Western blot. *P < 0.05