Table 2 Incidence risk of cancer for patients with moderate/severe TBI compared with patients with mild TBI
| Â | Before matching | After matching | ||||||
|---|---|---|---|---|---|---|---|---|
Variables | Mild TBI | Moderate/ severe TBI | Adjusted* HR (95% CI) | p value | Mild TBI | Moderate/severe TBI | Adjusted* HR (95% CI) | p value |
Cancer (%) | Cancer (%) | Cancer (%) | Cancer (%) | |||||
Overall | 710 (4.1) | 753 (4.2) | 1.14(1.03–1.27) | 0.0127 | 608(4.1) | 610(4.1) | 1.11(0.99–1.24) | 0.0751 |
Sex | ||||||||
 Male | 436 (4.4) | 506 (4.2) | 1.11(0.97–1.26) | 0.1241 | 406(4.4) | 377(4.1) | 1.04(0.90–1.19) | 0.6173 |
 Female | 274 (3.7) | 247 (4.1) | 1.21(1.02–1.44) | 0.0316 | 202(3.5) | 233(4.1) | 1.25(1.03–1.51) | 0.0219 |
Age | ||||||||
 20–35 | 92 (1.3) | 70 (1.1) | 1.08(0.79–1.48) | 0.6143 | 67 (1.1) | 60(1.0) | 1.19(0.84–1.68) | 0.3393 |
 36–45 | 167 (4.4) | 130 (3.5) | 0.98(0.78–1.24) | 0.8703 | 133(4.2) | 108(3.4) | 0.98(0.76–1.26) | 0.8518 |
 46–55 | 235 (6.4) | 288 (6.9) | 1.35(1.13–1.60) | 0.0008 | 211(6.3) | 252(7.5) | 1.29(1.07–1.55) | 0.0069 |
 55–65 | 216 (8.7) | 265 (7.4) | 1.06(0.89–1.28) | 0.5118 | 197(8.2) | 190(7.9) | 0.97(0.80–1.19) | 0.7947 |
Comorbidity | ||||||||
 HTN | 142 (8.3) | 159 (6.4) | 0.98(0.78–1.23) | 0.8546 | 129(8.1) | 118(6.4) | 0.92(0.71–1.18) | 0.5035 |
 DM | 85 (7.8) | 91 (5.9) | 0.92(0.68–1.24) | 0.5605 | 80(8) | 68(6.1) | 0.92(0.67–1.28) | 0.6340 |
 Hyperlipidemia | 67 (6.1) | 70 (5.2) | 1.06(0.75–1.50) | 0.7403 | 57(5.7) | 56(5.7) | 1.13(0.78–1.64) | 0.5106 |
 CAD | 29 (5.0) | 51 (6.8) | 1.51(0.95–2.41) | 0.0839 | 28(5.3) | 41(7.1) | 1.48(0.91–2.40) | 0.1151 |
 Renal disease | 11 (5.9) | 31 (8.0) | 2.17(1.08–4.36) | 0.0303 | 8(4.8) | 27(9.7) | 2.49(1.11–5.58) | 0.0273 |
 Stroke | 25 (6.4) | 57 (5.7) | 1.10(0.68–1.76) | 0.7254 | 23(6.3) | 36(4.9) | 1.01(0.59–1.71) | 0.9787 |