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Table 1 Demographic and clinical information of mild TBI and moderate/severe TBI patients

From: New diagnosis of cancer in mild and moderate/severe traumatic brain injury patients in a 12-year population-based study

  Before matching After matching
Variables Mild TBI
(N = 17,223)
Moderate/severe TBI
(N = 18,083)
p value Mild TBI
(N = 14,975)
Moderate/severe TBI
(N = 14,975)
p value
Sex
 Male 9891 (57.43) 12,028 (66.52)  < 0.0001 9227(61.62) 9254(61.80) 0.7482
 Female 7332 (42.57) 6055 (33.45)   5748(38.38) 5721(38.20)  
Age
 20–35 7283 (42.29) 6567 (36.32)  < 0.0001 6067(40.51) 6078(40.59) 0.9781
 36–45 3816 (22.16) 3753 (20.75)   3181(21.24) 3152(21.05)  
 46–55 3644 (21.16) 4183 (23.13)   3327(22.22) 3346(22.34)  
 55–65 2480 (14.40) 3580 (19.80)   2400(16.03) 2399(16.02)  
Comorbidity
 HTN 1719 (9.98) 2496 (13.80)  < 0.0001 1594(10.64) 1835(12.25)  < 0.0001
 DM 1084 (6.29) 1532 (8.47)  < 0.0001 1000(6.68) 1122(7.49) 0.0060
 Hyperlipidemia 1096 (6.38) 1335 (7.38) 0.0002 1001(6.68) 987(6.59) 0.7452
 CAD 583 (3.39) 749 (4.14) 0.0002 533(3.56) 579(3.87) 0.1598
 Renal disease 188 (1.09) 386 (2.13)  < 0.0001 165(1.10) 279(1.86)  < 0.0001
 Stroke 389 (2.26) 1003 (5.55)  < 0.0001 363(2.42) 742(4.95)  < 0.0001
Follow-up period (years) 10.64 ± 3.40 9.11 ± 3.16 0.0021 9.62 ± 3.66 8.90 ± 4.27  < 0.0001
Death
 Yes 1740 (10.10) 3376 (18.67)  < 0.0001 1559(10.41) 2654(17.72)  < 0.0001
 No 15,483 (89.90) 14,707 (81.33)   13,416(89.59) 12,321(82.28)  
Time to death (year) 5.93 ± 3.96 3.37 ± 3.77  < 0.0001 5.82 ± 3.93 3.56 ± 3.92  < 0.0001
Cancer
 Yes 710 (4.12) 753 (4.16) 0.8441 608(4.06) 610(4.07) 0.9533
 No 16,513 (95.88) 17,330 (95.84)   14,367(95.94) 14,365(95.93)  
Time to cancer (year)
Median (IQR)
5.08 (2.66–7.91) 4.75 (2.33–7.58) 0.0539 4.75(2.46–7.66) 4.96(2.58–7.92) 0.5378
  1. TBI traumatic brain injury, HTN hypertension, DM diabetes mellitus, CAD coronary artery disease, IQR interquartile range