| Before matching | After matching | ||||
---|---|---|---|---|---|---|
Variables | Mild TBI (N = 17,223) | Moderate/severe TBI (N = 18,083) | p value | Mild TBI (N = 14,975) | Moderate/severe TBI (N = 14,975) | p value |
Sex | ||||||
 Male | 9891 (57.43) | 12,028 (66.52) |  < 0.0001 | 9227(61.62) | 9254(61.80) | 0.7482 |
 Female | 7332 (42.57) | 6055 (33.45) |  | 5748(38.38) | 5721(38.20) |  |
Age | ||||||
 20–35 | 7283 (42.29) | 6567 (36.32) |  < 0.0001 | 6067(40.51) | 6078(40.59) | 0.9781 |
 36–45 | 3816 (22.16) | 3753 (20.75) |  | 3181(21.24) | 3152(21.05) |  |
 46–55 | 3644 (21.16) | 4183 (23.13) |  | 3327(22.22) | 3346(22.34) |  |
 55–65 | 2480 (14.40) | 3580 (19.80) |  | 2400(16.03) | 2399(16.02) |  |
Comorbidity | ||||||
 HTN | 1719 (9.98) | 2496 (13.80) |  < 0.0001 | 1594(10.64) | 1835(12.25) |  < 0.0001 |
 DM | 1084 (6.29) | 1532 (8.47) |  < 0.0001 | 1000(6.68) | 1122(7.49) | 0.0060 |
 Hyperlipidemia | 1096 (6.38) | 1335 (7.38) | 0.0002 | 1001(6.68) | 987(6.59) | 0.7452 |
 CAD | 583 (3.39) | 749 (4.14) | 0.0002 | 533(3.56) | 579(3.87) | 0.1598 |
 Renal disease | 188 (1.09) | 386 (2.13) |  < 0.0001 | 165(1.10) | 279(1.86) |  < 0.0001 |
 Stroke | 389 (2.26) | 1003 (5.55) |  < 0.0001 | 363(2.42) | 742(4.95) |  < 0.0001 |
Follow-up period (years) | 10.64 ± 3.40 | 9.11 ± 3.16 | 0.0021 | 9.62 ± 3.66 | 8.90 ± 4.27 |  < 0.0001 |
Death | ||||||
 Yes | 1740 (10.10) | 3376 (18.67) |  < 0.0001 | 1559(10.41) | 2654(17.72) |  < 0.0001 |
 No | 15,483 (89.90) | 14,707 (81.33) |  | 13,416(89.59) | 12,321(82.28) |  |
Time to death (year) | 5.93 ± 3.96 | 3.37 ± 3.77 |  < 0.0001 | 5.82 ± 3.93 | 3.56 ± 3.92 |  < 0.0001 |
Cancer | ||||||
 Yes | 710 (4.12) | 753 (4.16) | 0.8441 | 608(4.06) | 610(4.07) | 0.9533 |
 No | 16,513 (95.88) | 17,330 (95.84) |  | 14,367(95.94) | 14,365(95.93) |  |
Time to cancer (year) Median (IQR) | 5.08 (2.66–7.91) | 4.75 (2.33–7.58) | 0.0539 | 4.75(2.46–7.66) | 4.96(2.58–7.92) | 0.5378 |