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Table 1 Demographic and clinical information of mild TBI and moderate/severe TBI patients

From: New diagnosis of cancer in mild and moderate/severe traumatic brain injury patients in a 12-year population-based study

 

Before matching

After matching

Variables

Mild TBI

(N = 17,223)

Moderate/severe TBI

(N = 18,083)

p value

Mild TBI

(N = 14,975)

Moderate/severe TBI

(N = 14,975)

p value

Sex

 Male

9891 (57.43)

12,028 (66.52)

 < 0.0001

9227(61.62)

9254(61.80)

0.7482

 Female

7332 (42.57)

6055 (33.45)

 

5748(38.38)

5721(38.20)

 

Age

 20–35

7283 (42.29)

6567 (36.32)

 < 0.0001

6067(40.51)

6078(40.59)

0.9781

 36–45

3816 (22.16)

3753 (20.75)

 

3181(21.24)

3152(21.05)

 

 46–55

3644 (21.16)

4183 (23.13)

 

3327(22.22)

3346(22.34)

 

 55–65

2480 (14.40)

3580 (19.80)

 

2400(16.03)

2399(16.02)

 

Comorbidity

 HTN

1719 (9.98)

2496 (13.80)

 < 0.0001

1594(10.64)

1835(12.25)

 < 0.0001

 DM

1084 (6.29)

1532 (8.47)

 < 0.0001

1000(6.68)

1122(7.49)

0.0060

 Hyperlipidemia

1096 (6.38)

1335 (7.38)

0.0002

1001(6.68)

987(6.59)

0.7452

 CAD

583 (3.39)

749 (4.14)

0.0002

533(3.56)

579(3.87)

0.1598

 Renal disease

188 (1.09)

386 (2.13)

 < 0.0001

165(1.10)

279(1.86)

 < 0.0001

 Stroke

389 (2.26)

1003 (5.55)

 < 0.0001

363(2.42)

742(4.95)

 < 0.0001

Follow-up period (years)

10.64 ± 3.40

9.11 ± 3.16

0.0021

9.62 ± 3.66

8.90 ± 4.27

 < 0.0001

Death

 Yes

1740 (10.10)

3376 (18.67)

 < 0.0001

1559(10.41)

2654(17.72)

 < 0.0001

 No

15,483 (89.90)

14,707 (81.33)

 

13,416(89.59)

12,321(82.28)

 

Time to death (year)

5.93 ± 3.96

3.37 ± 3.77

 < 0.0001

5.82 ± 3.93

3.56 ± 3.92

 < 0.0001

Cancer

 Yes

710 (4.12)

753 (4.16)

0.8441

608(4.06)

610(4.07)

0.9533

 No

16,513 (95.88)

17,330 (95.84)

 

14,367(95.94)

14,365(95.93)

 

Time to cancer (year)

Median (IQR)

5.08 (2.66–7.91)

4.75 (2.33–7.58)

0.0539

4.75(2.46–7.66)

4.96(2.58–7.92)

0.5378

  1. TBI traumatic brain injury, HTN hypertension, DM diabetes mellitus, CAD coronary artery disease, IQR interquartile range