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Table 3 Hazard ratios for developing laryngeal cancer, according to the status of underweight and type 2 diabetes

From: Synergistic association between underweight and type 2 diabetes on the development of laryngeal cancer: a national population-based retrospective cohort study

  IR (per 1000 person-years) HR (95% CI)
Model 1 Model 2 Model 3
BMI, kg/m2
Type 2 diabetes (−)
   < 18.5 0.046 1.31 (1.09–1.57) 1.19 (0.99–1.42) 1.20 (1.00–1.44)
  18.5–22.9 0.040 1 (Reference) 1 (Reference) 1 (Reference)
  23–24.9 0.039 0.80 (0.73–0.88) 0.86 (0.78–0.94) 0.85 (0.77–0.93)
  25–29.9 0.035 0.72 (0.65–0.79) 0.79 (0.72–0.86) 0.76 (0.69–0.84)
   ≥ 30 0.019 0.66 (0.49–0.88) 0.72 (0.53–0.96) 0.67 (0.50–0.90)
BMI, kg/m2
Type 2 diabetes (+)
   < 18.5 0.275 2.37 (1.57–3.58) 2.09 (1.38–3.15) 2.02 (1.34–3.06)
  18.5–22.9 0.135 1.29 (1.11–1.48) 1.26 (1.09–1.45) 1.20 (1.04–1.39)
  23–24.9 0.104 1.02 (0.87–1.19) 1.07 (0.91–1.25) 1.00 (0.85–1.17)
  25–29.9 0.071 0.81 (0.70–0.94) 0.87 (0.75–1.01) 0.80 (0.69–0.94)
   ≥ 30 0.058 1.16 (0.81–1.68) 1.25 (0.87–1.81) 1.13 (0.78–1.64)
  1. Model 1 was adjusted for age, sex
  2. Model 2 was adjusted for age, sex, income status, smoking, alcohol consumption, and physical activity
  3. Model 3 was adjusted for age, sex, income status, smoking, alcohol consumption, physical activity, type 2 diabetes, hypertension, dyslipidemia, and anemia
  4. Abbreviations BMI Body mass index, CI Confidence interval, HR Hazard ratio, IR Incidence rate (1000 person-year)