Total No | Age (year) | Duration on TKIs (month) | IRIS molecular response (BCR-ABL1ISa) | Relative expressionb of hsa-miR-181a-5p (fold regulation) (collectively = 2.33 down-regulation) | Relative expressionb of hsa-miR-182-5p (fold regulation) (collectively = 2.08 up-regulation) | Relative expressionb of hsa-miR-26a-5p (fold regulation) (collectively = 2.39 up-regulation) |
---|---|---|---|---|---|---|
7 | 20–64 | 13–142 | >  10% | − 41.3405 to 2.0286 | −2.3320 to 9.5690 | −2.9519 to 12.6264 |
5 | 43–64 | 47–92 | ≤ 10% | −6.5409 to − 1.3561 | −1.5069 to 1.9297 | − 1.4556 to 2.6728 |
6 | 22–49 | 11–58 | ≤ 1% | −4.3154 to −1.0566 | − 1.1031 to 2.8252 | − 1.5819 to 3.2229 |
5 | 21–64 | 35–131 | ≤ 0.1% | −4.4367 to − 1.3009 | −1.1108 to 4.3120 | − 1.3581 to 11.0684 |
2 | 36–61 | 29–109 | MR4 | −1.9178 and 1.0501 | 4.0233 and 5.8904 | 5.8497 and 7.4559 |
2 | 42–60 | 26–75 | MR4.5 | −2.3776 and 1.1333 | 1.1474 and 7.1027 | 1.1083 and 2.7102 |
1 | 64 | 65 | undetermined | 1.5916 | 8.1589 | 13.9131 |
28 | 20-64c (46.04 ± 14.25)d | 11-142c (61.86 ± 36.33)d |  |  |  |  |