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Fig. 2 | BMC Cancer

Fig. 2

From: Novel pathological predictive factors for extranodal extension in oral squamous cell carcinoma: a retrospective cohort study based on tumor budding, desmoplastic reaction, tumor-infiltrating lymphocytes, and depth of invasion

Fig. 2

TB, TILs, and TB grading. a Immature stroma (DR-I), with a fibrotic stroma showing myxoid changes (H&E staining, × 200). b, c Mature stroma (DR-M), with no myxoid stroma or keloid-like collagen (H&E staining, × 200). a, b TILs with low lymphocyte infiltration (TILs-L ≤ 20%) (H&E staining, × 200). c TILs with high-to-low lymphocyte infiltration (TILs-H > 20%) (H&E staining, × 200). d TB classified as low (TB-L ≤ 10, arrowheads: budding) (H&E staining, × 400). e, f TB classified as high (TB-H > 10, arrowheads: budding) (H&E staining, × 200). DR-I, immature desmoplastic reaction; DR-M, mature desmoplastic reaction; H&E, hematoxylin and eosin; TB, tumor budding; TILs, tumor-infiltrating lymphocytes

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BMC Cancer

ISSN: 1471-2407

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