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Table 6 Factors associated with 90-day mortality after major resections with curative intent (R0 or R1); n = 1021a

From: Octogenarian patients with colon cancer – postoperative morbidity and mortality are the major challenges

 Factor

Dead within 90 days (%)

Unadjusted odds ratio (95% CI)

P value

Adjusted odds ratio (95% CI)

P value

Age (years)

     

< 65

1/233 (0.4)

   

65 – 74

8/327 (2.4)

├ 1 (reference)

 

1 (reference)

 

75 – 79

6/201 (3.0)

   

80 – 84

13/171 (7.6)

4.09 (1.91 to 8.77)

< 0.001

3.90 (1.60 to 9.52)

0.003

85 – 89

9/66 (13.6)

7.85 (3.29 to 18.73)

< 0.001

10.72 (3.74 to 30.71)

< 0.001

≥ 90

8/23 (34.8)

26.52 (9.77 to 72.01)

 

19.76 (5.53 to 70.5)

< 0.001

Female sex

 

0.54 (0.29 to 0.9976)

0.049

0.51 (0.24 to 1.08)

0.077

Calendar year

     

 1980-1989

12/175 (6.8)

1 (reference)

 

1 (reference)

 

 1990-1999

12/241 (5.0)

0.71 (0.31 to 1.62)

0.42

0.49 (0.17 to 1.38)

0.18

 2000-2009

10/334 (3.0)

0.42 (0.18 to 0.99)

0.048

0.29 (0.09 to 0.84)

0.022

 2010-2016

11/271 (4.1)

0.57 (0.25 to 1.33

0.20

0.45 (0.17 to 1.20)

0.11

ASA score

   

3.77 (2.12 to 6.69)

< 0.001

 1–2

10/591 (1.7%)

1 (reference)

 

1 (reference)

 

 3

20/395 (5.1%)

3.10 (1.43 to 6.69)

0.004

1.51 (0.63 to 3.59)

0.35

 4

15/35 (42.9%)

43.58 (17.44 to 108)

< 0.001

12.60 (4.26 to 37.25)

< 0.001

Emergency surgery

 

10.24 (5.50 to 19.09)

< 0.001

6.80 (3.24 to 14.28)

< 0.001

  1. aPatients included those with stages I-III colon cancer during 1980–2016; results are from a logistic regression analysis, with death as the dependent variable; unadjusted: performed with one covariate at a time; adjusted: performed with all listed covariates included simultaneously