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Table 6 Factors associated with 90-day mortality after major resections with curative intent (R0 or R1); n = 1021a

From: Octogenarian patients with colon cancer – postoperative morbidity and mortality are the major challenges

 Factor Dead within 90 days (%) Unadjusted odds ratio (95% CI) P value Adjusted odds ratio (95% CI) P value
Age (years)      
< 65 1/233 (0.4)    
65 – 74 8/327 (2.4) ├ 1 (reference)   1 (reference)  
75 – 79 6/201 (3.0)    
80 – 84 13/171 (7.6) 4.09 (1.91 to 8.77) < 0.001 3.90 (1.60 to 9.52) 0.003
85 – 89 9/66 (13.6) 7.85 (3.29 to 18.73) < 0.001 10.72 (3.74 to 30.71) < 0.001
≥ 90 8/23 (34.8) 26.52 (9.77 to 72.01)   19.76 (5.53 to 70.5) < 0.001
Female sex   0.54 (0.29 to 0.9976) 0.049 0.51 (0.24 to 1.08) 0.077
Calendar year      
 1980-1989 12/175 (6.8) 1 (reference)   1 (reference)  
 1990-1999 12/241 (5.0) 0.71 (0.31 to 1.62) 0.42 0.49 (0.17 to 1.38) 0.18
 2000-2009 10/334 (3.0) 0.42 (0.18 to 0.99) 0.048 0.29 (0.09 to 0.84) 0.022
 2010-2016 11/271 (4.1) 0.57 (0.25 to 1.33 0.20 0.45 (0.17 to 1.20) 0.11
ASA score     3.77 (2.12 to 6.69) < 0.001
 1–2 10/591 (1.7%) 1 (reference)   1 (reference)  
 3 20/395 (5.1%) 3.10 (1.43 to 6.69) 0.004 1.51 (0.63 to 3.59) 0.35
 4 15/35 (42.9%) 43.58 (17.44 to 108) < 0.001 12.60 (4.26 to 37.25) < 0.001
Emergency surgery   10.24 (5.50 to 19.09) < 0.001 6.80 (3.24 to 14.28) < 0.001
  1. aPatients included those with stages I-III colon cancer during 1980–2016; results are from a logistic regression analysis, with death as the dependent variable; unadjusted: performed with one covariate at a time; adjusted: performed with all listed covariates included simultaneously