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Table 2 Univariate and multivariate analysis of risk score and clinical factors with OS in the training cohort and validation cohort of TCGA and external validation cohort

From: Comprehensive analysis of tumor immune microenvironment and prognosis of m6A-related lncRNAs in gastric cancer

Risk factor Training cohort in TCGA (N = 260) Validation cohort in TCGA (N = 111) External cohort (N = 35)
  Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
  Hazard ratio (95% CI) P-value Hazard ratio (95% CI) P-value Hazard ratio (95% CI) P-value Hazard ratio (95% CI) P-value Hazard ratio (95% CI) P-value Hazard ratio (95% CI) P-value
Age 1.048 (1.021–1.075) < 0.001 1.058 (1.031–1.086) < 0.001 1.002 (0.977–1.028) 0.890 1.013 (0.985–1.042) 0.360 1.214 (0.321–2.312) 0.235 1.032 (0.231–2.913) 0.451
Gender 1.240 (0.772–1.993) 0.374 1.411 (0.858–2.319) 0.175 1.304 (0.728–2.335) 0.371 1.202 (0.667–2.169) 0.540 1.152 (0.489–2.182) 0.552 0.924 (0.451–3.521) 0.461
Grade 1.638 (1.031–2.601) 0.037 1.754 (1.080–2.846) 0.023 1.117 (0.676–1.845) 0.665 1.104 (0.655–1.861) 0.711 3.456 (1.224–5.050) 0.024 2.341 (0.219–7.121) 0.034
Stage 1.457 (1.099–1.933) 0.009 1.483 (1.085–2.027) 0.014 1.671 (1.209–2.308) 0.002 1.813 (1.281–2.565) < 0.001 2.341 (0.512–5.641) 0.235 1.425 (0.248–7.214) 0.810
riskScore 1.674 (1.395–2.008) < 0.001 1.798 (1.484–2.179) < 0.001 1.513 (1.102–2.731) 0.007 1.872 (1.723–2.098) 0.04 2.424 (1.516–3.124) 0.013 1.915 (1.529–2.942) 0.040