From: Pan-cancer analysis identifies BIRC5 as a prognostic biomarker
Cancer type and pan-organ system | Cohort | Number of samples | ||||
---|---|---|---|---|---|---|
Genetic alterationsa | RNA-seqa | Co-expressiona | KM plotter | |||
Cancer tissue | Normal tissue | |||||
Central nervous system | ||||||
 Glioblastoma multiforme | GBM | 592 | 166 | 5 | 145 |  |
 Brain lower grade carcinoma | LGG | 514 | 530 | 0 | 511 |  |
Endocrine | ||||||
 Adrenocortical carcinoma | ACC | 91 | 79 | 0 | 78 |  |
 Thyroid carcinoma | THCA | 500 | 496 | 58 | 480 |  |
Gastrointestinal | ||||||
 Cholangiocarcinoma | CHOL | 36 | 36 | 9 | 36 |  |
 Colon adenocarcinoma | COADb | 594 | 191 | 0 | 524 |  |
 Rectum adenocarcinoma | READ | 72 | 0 |  | ||
 Esophageal Adenocarcinoma | ESCAc | 182 | 185 | 11 | 181 |  |
 Esophageal squamous carcinoma | ||||||
 Liver hepatocellular carcinoma | LIHC | 372 | 147 | 50 | 348 |  |
 Pancreatic adenocarcinoma | PAAD | 184 | 56 | 0 | 168 |  |
 Stomach adenocarcinoma | STADf | 440 | 415 | 35 | 407 | 875 |
Gynecologic | ||||||
 Breast invasive carcinoma | BRCA | 1084 | 1026 | 108 | 994 | 1879 |
 Cervical squamous cell carcinoma | CESCd | 297 | 159 | 0 | 275 |  |
 Ovarian serous cystadenocarcinoma | OV | 584 | 265 | 0 | 201 | 1656 |
 Uterine corpus endometrial carcinoma | UCEC | 529 | 369 | 0 | 507 |  |
Head and neck | ||||||
 Head and neck squamous cell carcinoma | HNSC | 523 | 425 | 42 | 488 |  |
Hematologic and lymphatic malignancies | ||||||
 Diffuse Large B-cell Lymphoma | DLBC | 41 | 48 | 0 | 37 |  |
 Acute myeloid leukemia | LAML | 200 | 173 | 0 | 165 |  |
 Thymoma | THYM | 123 | 120 | 0 | 119 |  |
Melanocytic | ||||||
 Skin cutaneous melanoma | SKCM | 444 | 472 | 0 | 363 |  |
 Uveal melanoma | UVM | 80 | 80 | 0 | 80 |  |
Neural crest-derived | ||||||
 Pheochromocytoma and paraganglioma | PCPG | 178 | 184 | 3 | 161 |  |
Soft tissue | ||||||
 Sarcoma | SARC | 255 | 105 | 0 | 251 |  |
 Uterine carcinosarcoma | UCS | 57 | 57 | 0 | 56 |  |
Thoracic | ||||||
 Lung adenocarcinoma | LUADe | 566 | 490 | 58 | 503 | 1925 |
 Lung squamous cell carcinoma | LUSCe | 487 | 482 | 50 | 466 | |
 Mesothelioma | MESO | 87 | 87 | 0 | 82 |  |
Urologic | ||||||
 Bladder urothelial carcinoma | BLCA | 411 | 223 | 19 | 402 |  |
 Kidney chromophobe | KICH | 65 | 66 | 25 | 65 |  |
 Kidney renal clear cell carcinoma | KIRC | 511 | 507 | 72 | 352 |  |
 Kidney renal papillary cell carcinoma | KIRP | 283 | 161 | 30 | 274 |  |
 Prostate adenocarcinoma | PRAD | 494 | 498 | 52 | 488 |  |
 Testicular germ cell tumors | TGCT | 145 | 156 | 0 | 144 |  |
Total | Â | 8812 | 8526 | 627 | 9351 | 6335 |