Fig. 2

Real-time cell growth analysis. Human liver cancer cells Huh7 (A, B) and Mahlavu (MV) (C, D) were treated with the Sorafenib, PI3Ki-α and PI3Ki-β alone or in combination with increasing concentrations as indicated. Cell index measurements were obtained by RT-CES software. DMSO was used as negative control A B. 72 h of the percent growth inhibition values were used to calculate drug interactions with The SynergyFinder web application. Positive delta score reflects synergistic and negative score reflects antagonistic drug interactions. Experiments were performed in triplicate