Skip to main content
Fig. 3 | BMC Cancer

Fig. 3

From: Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies—the role of HAS2, SHB and HBEGF

Fig. 3

Identification of candidate biomarkers for afatinib treatment in NCI-N87 and MKN1 cells. a 62/335 genes were regulated after 4 h/24 h afatinib treatment in NCI-N87 and MKN1 cells. The 45 genes that were regulated after 4 h and 24 h afatinib treatment in NCI-N87 and MKN1 cells were identified as candidate biomarkers. b The 45 genes which were regulated in NCI-N87 as well as in MKN1 cells after 4 h and 24 h afatinib treatment were analyzed using the STRING Tool. The colors indicate different functional associations (green: textmining, black: co-expression, blue: from curated databases, pink: experimentally determined, purple: protein homology)

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us