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Table 2 Prognostic factor analysis for overall survival and progression-free survival

From: The survival strength of younger patients in BCLC stage 0-B of hepatocellular carcinoma: basing on competing risk model

Variables

Overall survival

Progression-free survival

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

HR

95%CI

p.value

HR

95%CI

p.value

HR

95%CI

p.value

HR

95%CI

p.value

Sex[Female]

0.93

0.76–1.1

0.45

   

0.93

0.78–1.1

0.44

   

Age group[≤45y]

0.69

0.52–0.91

0.0093

0.74

0.55–0.98

0.037

0.68

0.53–0.87

0.0023

0.71

0.55–0.91

0.008

Alcohol abuse[alcohol]

1.2

0.98–1.4

0.079

   

1.1

0.95–1.3

0.21

   

Family history of HCC[No]

0.75

0.45–1.3

0.28

   

0.91

0.59–1.4

0.65

   

Tumor size[> 5 cm]

2.4

2–2.9

< 0.001

2.46

2.05–2.95

< 0.001

2.4

2–2.8

< 0.001

2.41

2.04–2.85

< 0.001

PVTT at baseline[Yes]

2

0.82–4.8

0.13

   

1.3

0.55–3.2

0.53

   

WBC (10^9/L) [High>4]

0.97

0.83–1.1

0.75

   

0.95

0.82–1.1

0.46

   

PLT(10^9/L) [High> 100]

0.95

0.81–1.1

0.56

   

0.99

0.85–1.1

0.89

   

ALT(U/L) [High> 50]

1.2

0.96–1.4

0.12

   

1.2

1–1.4

0.035

   
  1. A Cox proportional hazards regression model for OS and PFS was used. The reference category for each categorical variable is in the square brackets in first column. HR, hazard ratio; OS, overall survival; PFS, progression-free survival; PVTT, portal vein tumor thrombus; WBC, white blood cell; PLT, platelet; ALT, alanine aminotransferase
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BMC Cancer

ISSN: 1471-2407

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