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Table 3 The expression rates of p-AKT, p-mTOR, p-S6 and p-4E-BP1 in the PTEN loss group and normal group

From: The PI3K/AKT/mTOR signaling pathway is aberrantly activated in primary central nervous system lymphoma and correlated with a poor prognosis

Protein

PTEN loss

PTEN normal

P value

(n = 7)

(n = 30)

p-AKT

100% (7/7)

56.7% (17/30)

0.038*

p-mTOR

100% (7/7)

70.0% (21/30)

0.160

p-S6

100% (7/7)

76.7% (23/30)

0.306

p-4E-BP1

57.1% (4/7)

73.3% (22/30)

0.403

  1. Note: * represents a statistically significant difference
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BMC Cancer

ISSN: 1471-2407

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