Fig. 4From: The PI3K/AKT/mTOR signaling pathway is aberrantly activated in primary central nervous system lymphoma and correlated with a poor prognosisDetection of the loss of PTEN by FISH in PCNSL samples (n = 37). DAPI nuclear staining is shown as blue fluorescent signal. The red fluorescent signal represents the PTEN gene probe, and the green fluorescent signal represents the centromere probe. The ratio of the PTEN signal to centromere signal was less than 0.8 indicating the deletion of PTEN geneBack to article page